Drug Class: Nootropic & Neuroprotective Peptide
Composition: Semax
Dosage: 5 mg/vial
Form: Lyophilized Powder
Unit: 2 mL Vial
Brand: Peptide Hubs
For Intranasal or Subcutaneous Administration
For bodybuilders, athletes, and high-achievers in the USA, mental edge is the ultimate performance enhancer. Peptide Hubs Semax delivers a pharmaceutical-grade cognitive boost that transcends ordinary nootropics. Developed by Russian scientists from the Institute of Molecular Genetics, this 5 mg vial of pure, lyophilized peptide represents a breakthrough in neuroenhancement. Unlike stimulants that provide fleeting energy followed by a crash, Semax works by optimizing your brain's natural chemistry, providing clean, sustained focus, enhanced memory, and powerful neuroprotection. Whether you're pushing through a grueling workout, studying complex material, or needing laser-sharp concentration, Semax is your prescription for unparalleled mental performance.
Semax is a synthetic heptapeptide (Met-Glu-His-Phe-Pro-Gly-Pro) based on a fragment of the adrenocorticotropic hormone (ACTH). However, it lacks the hormonal activity of ACTH and instead functions as a potent nootropic and neuroprotective agent. Its primary mechanism involves modulating the brain's neurotransmitter systems, particularly by increasing the levels of Brain-Derived Neurotrophic Factor (BDNF), a key protein responsible for neuron growth, synaptic plasticity, and cognitive function. Research cited in the National Library of Medicine demonstrates that Semax enhances learning and memory, improves attention, and protects brain cells from oxidative stress and ischemia. It also influences dopamine, serotonin, and GABA systems, creating a unique state of calm, focused alertness that is ideal for high-pressure situations and demanding cognitive tasks.
The effects of Semax are both immediate and cumulative, offering acute cognitive enhancement while building long-term brain health.
Semax is highly versatile and is most commonly administered intranasally for rapid effects, though subcutaneous injection is also effective. It is supplied as a lyophilized powder that must be reconstituted with Bacteriostatic Water.
Reconstitution Guide:
Dosing Recommendations:
Semax is typically cycled to prevent potential receptor downregulation and maintain its efficacy. Common cycles are 2-4 weeks on, followed by a 1-2 week break. It stacks synergistically with other peptides to create powerful cognitive and physical enhancement protocols.
Semax is renowned for its exceptional safety profile and is generally very well-tolerated. Side effects are rare, mild, and typically transient.
There are no known serious side effects or toxicities associated with Semax. It is non-addictive and does not cause withdrawal symptoms. Its safety profile is a key reason for its popularity and widespread use.
Name: Semax
Drug Class: Nootropic & Neuroprotective Peptide
Other common names and terms: Heptapeptide Semax
Active Life: 2-4 hours (intranasal), longer for SubQ
Detection Time: Not established, likely short
Chemical Structure: Heptapeptide (Met-Glu-His-Phe-Pro-Gly-Pro)
Common Doses: 200 mcg - 1000 mcg daily, split into 1-2 doses
Blood pressure: May cause a very slight, transient increase
Acne: None
Water retention: None
Aromatisation: Does not aromatize
Liver toxicity: None
Decrease HPTA function: No
The effects of Semax are notably fast-acting, especially when administered intranasally. Most users report feeling a change in mental state within 5 to 15 minutes after administration. The initial sensation is often a "clearing of brain fog" followed by a gradual increase in focus and alertness that peaks around 1-2 hours post-dose. The effects can last for 4-8 hours. With subcutaneous injection, the onset is slightly slower (20-40 minutes) but the duration may be extended. The cumulative neuroprotective and memory-enhancing benefits develop over consistent use of 1-2 weeks.
These are related but distinct peptides. Semax is primarily a stimulant nootropic—it increases focus, energy, and alertness. Selank is primarily an anxiolytic—it calms you down and reduces anxiety while maintaining clarity. They are often stacked together for balanced effects. N-Acetyl Semax Amidate is an advanced analog of Semax. The "N-Acetyl" and "Amidate" modifications make it more resistant to enzymatic breakdown, resulting in a longer half-life, greater potency (estimated 5-10x stronger), and a more prolonged effect. For new users, standard Semax is a great starting point, while experienced users may prefer the enhanced performance of the amidated version.
Absolutely. Semax is an exceptional non-stimulant pre-workout. Its ability to enhance focus and concentration directly improves mind-muscle connection, allowing for more intense and productive training sessions. You'll be able to maintain better form, push through mental barriers, and stay fully engaged with your workout without the jitters, crash, or cardiovascular stress associated with high-caffeine pre-workouts. A dose of 300-600 mcg intranasally about 20-30 minutes before training is ideal. It can also be combined with a stimulant-based pre-workout for those who need the extra energy, as it can help smooth out the stimulant's edge.
Semax has an excellent safety profile and is well-tolerated with daily use. However, to prevent any potential tolerance or receptor desensitization from developing, it is generally recommended to cycle its use. A common and effective protocol is to use Semax for 2-4 weeks consecutively, followed by a break of 1-2 weeks. This "off" period allows your brain's neurotransmitter systems to reset, ensuring that Semax remains highly effective when you resume your cycle. Some users choose to use it only on weekdays or on days requiring peak mental performance.
Yes, indirectly but significantly. Semax does not directly stimulate dopamine release like some drugs, but its effects create a mental environment highly conducive to motivation. By clearing brain fog, enhancing focus, and providing clean mental energy, it removes the common barriers to starting and persisting with tasks. When your mind is clear and you can concentrate without distraction, initiating action and maintaining drive becomes much easier. Many users report a marked increase in productivity and a reduced tendency toward procrastination, making it easier to stick to training schedules, diet plans, and other goals.
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Drug Class: Synthetic Peptide Nootropic
Composition: Semax
Dosage: 5 mg/vial
Form: Lyophilized Powder
Unit: 2 mL Vial
Brand: Dragon Pharma
Laboratory Test: View Lab Report
For Subcutaneous or Intranasal Administration After Reconstitution
For Intramuscular Injection
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Mixed Dosage: 350 mg/1 mL
Unit: 10 mL Multidose Vial
Manufactured by Kalpa Pharmaceuticals