SS-31 50 mg

SS-31 50 mg: The Mitochondrial Guardian for Enhanced Endurance and Cellular Recovery

For athletes pushing the boundaries of human performance, the true limit often lies not in the muscles themselves, but within the microscopic powerplants that fuel them: the mitochondria. SS-31 (also known as Bendavia or MTP-131) represents a groundbreaking class of peptide therapy that operates at this fundamental cellular level. Sourced from Peptide Hubs in a high-potency 50 mg vial, SS-31 is a first-in-class mitochondrial-targeted peptide designed to protect these vital organelles from oxidative stress and dysfunction. When you buy SS-31 USA, you are investing in the very foundation of cellular energy production, with profound implications for endurance, recovery, and overall athletic longevity.

What is SS-31?

SS-31 is a novel, water-soluble tetrapeptide (D-Arg-Dmt-Lys-Phe-NH2) that possesses a unique chemical property: it selectively accumulates several hundred-fold within the inner mitochondrial membrane. This is the epicenter of cellular energy production through oxidative phosphorylation, but it's also the primary site where reactive oxygen species (ROS) are generated. SS-31's mechanism is elegantly targeted; it binds to cardiolipin, a phospholipid essential for the function of key proteins in the electron transport chain. A seminal study in the Journal of Clinical Investigation demonstrated that SS-31 protects mitochondrial structure and function by preventing the peroxidation of cardiolipin, thereby reducing electron leak and ROS production. Unlike systemic antioxidants, SS-31 works with surgical precision right where damaging free radicals are born, making it one of the most efficient cellular protectors available for research.

SS-31 Effects

The effects of SS-31 are systemic and foundational, stemming from its ability to optimize the function of mitochondria in every cell:

• Enhanced Endurance and Reduced Fatigue: By improving the efficiency of ATP (energy) production and reducing energy waste as heat and ROS, SS-31 helps delay the onset of muscular fatigue. Researchers report an ability to sustain higher training intensities for longer durations.
• Accelerated Post-Exercise Recovery: Intense exercise generates a flood of mitochondrial ROS, contributing to muscle damage and soreness. By scavenging these ROS at their source, SS-31 significantly reduces oxidative damage, leading to faster recovery between training sessions.
• Improved Cellular Health and Longevity: Mitochondrial dysfunction is a hallmark of aging and cellular decay. SS-31 helps maintain youthful mitochondrial function, which is crucial for the long-term health of all tissues, including the heart, brain, and skeletal muscle.
• Cardioprotective Benefits: The heart is one of the most mitochondrially dense organs. SS-31 has been extensively researched for its ability to protect cardiac tissue from ischemic damage and improve overall cardiac efficiency, which can enhance cardiovascular performance during exercise.
• Reduced Exercise-Induced Apoptosis: Severe oxidative stress can trigger programmed cell death (apoptosis) in muscle cells. By maintaining mitochondrial integrity, SS-31 helps protect muscle cells from this form of exercise-induced damage.

SS-31 Dosage

For research purposes, SS-31 is typically administered via subcutaneous injection. Its targeted mechanism allows for relatively low but potent dosing. Common research dosages in preclinical models translate to a human equivalent range of approximately 0.5 mg to 2.0 mg per day for a 70 kg individual. A standard research starting point is often 1.0 mg per day. The high-capacity 50 mg vial from Peptide Hubs provides an extensive supply for long-term research protocols. The lyophilized powder must be reconstituted with Bacteriostatic Water (Bac Water). For precise measurement of these small doses, the use of an insulin syringe is mandatory. Administration can be done once daily, with many researchers preferring a morning or pre-workout injection to maximize protection during periods of high metabolic demand.

SS-31 Cycle

SS-31 is well-suited for both short-term performance blocks and long-term health-spanning protocols. For athletic performance, cycles of 8-12 weeks are common, often aligned with intense training periods or competition seasons. For general mitochondrial support and anti-aging research, longer cycles of 3-6 months are typical. SS-31's excellent safety profile supports extended use. It can be powerfully stacked with other compounds that support cellular energy and recovery:

• MOTS-c 10 mg: Another mitochondrial-derived peptide that regulates metabolic homeostasis. Stacking MOTS-c with SS-31 provides a dual approach: SS-31 protects mitochondrial function, while MOTS-c optimizes how mitochondria communicate with and influence cellular metabolism.
• NAD+ 100 mg: The essential cofactor for sirtuins and a key player in mitochondrial biogenesis. Supporting NAD+ levels complements SS-31's protective effects by promoting the creation of new, healthy mitochondria.
• Humanin 10 mg: A mitochondrial-derived peptide with potent cytoprotective effects against stress and apoptosis. The combination of SS-31 and Humanin represents a powerful strategy for comprehensive cellular defense.
• AICAR 50 mg: This AMPK activator simulates the metabolic effects of endurance exercise. Stacked with SS-31, it can enhance mitochondrial efficiency and endurance capacity through complementary pathways.
• Bac Water: The essential sterile solvent required for the safe reconstitution of SS-31 and other lyophilized peptides.

Possible Side Effects

SS-31 has demonstrated an exceptional safety profile in extensive clinical trials for various conditions. Due to its highly targeted mechanism and natural peptide structure, reported side effects are rare and typically mild. The most common observation is a transient, mild sensation of flushing or warmth shortly after injection, which resolves quickly. There is no evidence of HPTA suppression, liver toxicity, or interactions with other hormonal systems. Its action is purely on cellular energetics and oxidative stress. As with any injectable, ensuring product purity and sterility is paramount, which is a core commitment of Peptide Hubs.

SS-31 vs. Traditional Antioxidants

This is a critical distinction. Common antioxidants like Vitamin C or E work systemically and can be consumed in neutralizing free radicals throughout the body. However, they do not effectively penetrate the mitochondrial matrix. SS-31's revolutionary advantage is its ability to cross both the cell and mitochondrial membranes to act precisely where the majority of cellular ROS are generated. This makes it vastly more efficient on a per-molecule basis. While traditional antioxidants are like pouring water on a fire from the outside, SS-31 operates like a built-in sprinkler system directly inside the building where the fire starts.

Conclusion

SS-31 stands at the pinnacle of mitochondrial medicine, offering a sophisticated, targeted approach to enhancing cellular energy production and resilience. For the serious athlete or longevity researcher, optimizing mitochondrial function is no longer a vague concept but a tangible target thanks to peptides like SS-31. Its ability to directly protect the machinery of energy production translates to measurable benefits in endurance, recovery, and overall cellular health. When you decide to buy SS-31 USA, the integrity of the compound is non-negotiable. Peptide Hubs SS-31 is produced to the highest standards of purity, with every 50 mg vial verified for accuracy and biological activity, ensuring your research into the frontiers of cellular performance is built on a foundation of quality and reliability.

SS-31 Profile

Name: SS-31 (Elamipretide)
Drug Class: Mitochondrial-Targeted Antioxidant Peptide
Other common names and terms: Bendavia, MTP-131, Elamipretide
Active Life: Several hours
Detection Time: Not established; presumed short due to peptide nature
Chemical Structure: D-Arg-Dmt-Lys-Phe-NH2 (a synthetic tetrapeptide)
Common Doses: 0.5 - 2.0 mg per day (for research purposes)
Blood pressure: No significant impact reported; may have cardioprotective benefits
Acne: Not associated
Water retention: Not associated
Aromatisation: Does not aromatize
Liver toxicity: None reported; may be hepatoprotective
Decrease HPTA function: No evidence of HPTA suppression