S4 25 mg

Dragon Pharma S4: The Original Hardening SARM for Lean Muscle and Vascularity

Dragon Pharma S4, known scientifically as Andarine, is one of the pioneering Selective Androgen Receptor Modulators (SARMs) that set the standard for muscle hardening and fat loss. As one of the first SARMs developed and extensively researched, S4 has a well-documented profile of producing dramatic increases in muscle density, striations, and vascularity. Its unique mechanism provides strong anabolic effects while significantly reducing androgenic side effects compared to traditional steroids. While it is most famous for its potential visual side effects, which are manageable for most users, its ability to carve out a dry, hard, and vascular physique is undeniable. Dragon Pharma's 25mg tablet formulation offers the perfect dosage for the proven dosing protocol, making it an excellent choice for bodybuilders and athletes seeking that next level of conditioning.

Powerful Effects of S4 (Andarine)

S4 works by selectively binding to androgen receptors in muscle and bone tissue. Its effects are particularly pronounced during cutting and recomposition phases, where it helps preserve and even build lean tissue while shedding fat.

• Extreme Muscle Hardness and Density: S4 is renowned for its ability to create a dry, grainy look. It enhances muscle density by pulling water from between the muscle fibers and the skin, resulting in a hard, defined appearance that is highly sought after during pre-contest preparation.
• Significant Fat Loss: Andarine increases metabolic rate and promotes lipolysis (fat breakdown). It helps the body utilize stored fat as an energy source, leading to noticeable reductions in body fat, particularly in stubborn areas like the lower abdomen and love handles.
• Dramatic Vascularity: As subcutaneous fat decreases and water retention is minimized, vascularity becomes exceptionally prominent. Users often experience enhanced vein visibility across the entire body, contributing to a shredded, professional look.
• Solid Strength Gains: While not primarily a bulking SARM, S4 provides consistent and noticeable strength increases. This allows users to maintain training intensity while in a calorie deficit, which is crucial for preserving muscle mass during a cut.
• Improved Bone Density: Like other SARMs, S4 has a strong affinity for bone tissue. It can increase bone mineral density, which is beneficial for long-term joint health and injury prevention, especially important for heavy lifters.
• Muscle Preservation: S4 is extremely effective at preventing muscle catabolism. During a cutting phase, it sends a strong anabolic signal to the muscles, ensuring that the weight lost comes from fat stores and not hard-earned muscle tissue. Research on the NIH's PubChem database details Andarine's chemical structure and selective action.

Recommended S4 Dosage and Protocol

S4 has a relatively short half-life of approximately 4-6 hours. To maintain stable blood levels and manage side effects, a specific dosing protocol is recommended.

• Beginner Dosage: 25 mg per day, split into two doses of 12.5mg (half a tablet) taken approximately 8-10 hours apart.
• Intermediate Dosage: 50 mg per day, split into two doses of 25mg (one tablet) taken approximately 8-10 hours apart. This is the most common and effective dose.
• Advanced Dosage: 75 mg per day, split into three doses of 25mg taken approximately 6-8 hours apart. Doses above 75mg significantly increase the risk and intensity of visual side effects.

The 5-Day On, 2-Day Off Protocol: To help manage and potentially reverse visual side effects, many users employ a cycle where they take S4 for five consecutive days, followed by two days off. This break can allow the eyes to recover and reduce the accumulation of side effects. Cycle length is typically 8-12 weeks. A Post Cycle Therapy (PCT) is recommended after cycles longer than 8 weeks or at doses above 50mg per day.

Effective S4 Cycle Stacking

S4 stacks exceptionally well with other compounds to enhance its cutting effects or to create a powerful recomping stack.

• The Ultimate Cutting Stack: Combine S4 with GW501516 (Cardarine). Cardarine provides the endurance for intense cardio sessions and enhances fat oxidation, while S4 preserves muscle and creates hardness. This is a classic and highly effective cutting combination.
• Strength and Hardening Stack: Stack S4 with MK-2866 (Ostarine). Ostarine provides joint support and additional lean mass gains, creating a well-rounded stack that improves strength, hardness, and recovery.
• Aggressive Fat Loss Stack: For extreme fat loss, stack S4 with SR9009 (Stenabolic) and T3 (Cytomel). This stack dramatically increases metabolic rate and endurance while S4 ensures all lost weight is pure fat, not muscle.
• Vision Support Stack: To proactively support eye health while using S4, consider stacking it with a vision support supplement containing Lutein and Zeaxanthin. While not a Dragon Pharma product, this is a prudent addition for any user concerned about the visual side effects.
• Post Cycle Therapy Support: After an S4 cycle, a standard PCT with Nolvadex (Tamoxifen) or Clomid (Clomiphene) for 4 weeks is recommended to restore natural testosterone production efficiently.

Possible Side Effects of S4

While S4 is selective and generally well-tolerated, it does have a unique and well-documented side effect profile that users must be aware of.

• Visual Disturbances (The "Yellow Vision" Effect): This is S4's signature side effect. It can cause a slight yellow tint to vision, difficulty adjusting to darkness, and a perception that lights are brighter than usual (halos). This is due to S4's interaction with photoreceptors in the eyes and is dose-dependent and reversible. The 5-on/2-off protocol and staying under 75mg/day help manage this.
• Testosterone Suppression: S4 is suppressive to natural testosterone production, though typically less so than stronger SARMs like S-23 or LGD 4033. A PCT is still necessary after most cycles to ensure a full recovery.
• Negative Lipid Profile Impact: Like most anabolic compounds, S4 can negatively affect cholesterol by lowering HDL (good) cholesterol. A heart-healthy diet rich in omega-3s is advised.
• Mild Androgenic Side Effects: At higher doses, some users who are genetically predisposed may experience mild acne or accelerated hair loss.
• No Liver Toxicity: S4 is not liver toxic and does not carry the 17-alpha alkylation that makes oral steroids hepatotoxic. It is considered safe for the liver.
• No Estrogenic Activity: S4 does not aromatize (convert to estrogen), so users do not have to worry about estrogen-related side effects like gynecomastia or water retention.

Why Dragon Pharma S4 is a Trusted Choice

In the world of research chemicals, consistency and accuracy are paramount. Dragon Pharma's commitment to quality manufacturing ensures that each 25mg tablet contains the precise amount of active Andarine needed to follow established and effective dosing protocols. You can confidently split tablets for your 12.5mg doses or take a full tablet knowing you are administering a known quantity. This reliability allows for predictable results and manageable side effects, making Dragon Pharma S4 the smart choice for athletes who want to leverage the powerful hardening effects of this classic SARM without the guesswork.

S4 Profile

Name: Andarine, S-4
Drug Class: SARM (Selective Androgen Receptor Modulator)
Other common names and terms: Andarine, S-4, GTx-007
Active Life: 4-6 hours
Detection Time: ~3 weeks
Chemical Structure: N-(4-cyano-3-(trifluoromethyl)phenyl)-2-((2R)-2-(2,2,2-trifluoroacetamido)-3-(4-cyanophenoxy)propanamido)acetamide
Common Doses: 25-75 mg/day (split doses)
Blood pressure: Typically neutral
Acne: Rare/Mild
Water retention: None (causes dryness)
Aromatisation: No
Liver toxicity: No
Decrease HPTA function: Yes (mildly to moderately suppressive)