S 23 10 mg S 23 10 mg S 23 10 mg
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S 23 10 mg

Drug Class: SARM (Selective Androgen Receptor Modulator)
Composition: Mastorin (S-23)
Dosage: 10 mg/tablet
Form: Oral Tablets
Unit: 100 Tablets
Brand: Dragon Pharma
Laboratory Test: View Latest Lab Report
For Oral Administration

$60.00
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U.S. Domestic

Dragon Pharma S-23: The Most Potent SARM for Extreme Hardening and Fat Loss

Dragon Pharma S-23, also known as Mastorin, stands at the absolute pinnacle of SARM potency and is considered one of the most powerful compounds in its class. It is not for the faint of heart or novice user. S-23 possesses strong anabolic and androgenic properties, with a unique ability to act as a partial agonist of the progesterone receptor, setting it apart from other SARMs. This complex mechanism of action results in dramatic increases in muscle density, extreme fat loss, and unparalleled hardening effects that rival traditional anabolic steroids. Dragon Pharma's 10mg tablet delivers this formidable compound with precision, and our latest third-party lab test confirming over 12mg of active ingredient per tablet ensures you are utilizing one of the most potent and reliable anabolic agents available to advanced bodybuilders today.

Powerful Effects of S-23 (Mastorin)

S-23's effects are profound and rapid, making it a favorite for pre-contest preparation and aggressive cutting phases. Its multi-receptor activity creates a unique and powerful anabolic environment.

  • Extreme Muscle Hardness and Density: S-23 is renowned for its ability to create a dry, grainy, and hard physique. It pulls water from between the muscle fibers and the skin, resulting in a level of muscularity and detail that is difficult to achieve with other SARMs.
  • Dramatic Fat Loss: S-23 has a significant impact on metabolic rate and fat oxidation. It promotes a shift in fuel utilization, encouraging the body to burn stored fat for energy, leading to rapid and visible fat loss, particularly in stubborn areas.
  • Substantial Strength and Power Increases: Users experience explosive strength gains, often surpassing those seen with other SARMs. This allows for more intense training sessions, further stimulating muscle growth and fat loss.
  • Pronounced Vascularity: As subcutaneous water is reduced and body fat decreases, vascularity becomes exceptionally prominent. Users often see veins in new areas, contributing to a shredded, professional-level appearance.
  • Androgenic and Progestogenic Activity: Unlike milder SARMs, S-23 exhibits significant androgenic and progestogenic properties. This can contribute to its powerful effects but also increases the risk of androgenic side effects and requires careful cycle management.
  • Muscle Preservation in a Calorie Deficit: Its potent anabolic signal makes S-23 exceptionally effective at preserving lean muscle tissue during aggressive cutting phases, ensuring that the weight you lose comes from fat, not muscle.

Recommended S-23 Dosage

S-23 has a half-life of approximately 12-16 hours, making twice-daily dosing ideal for stable blood levels. Due to its extreme potency and significant side effect profile, dosing must be approached with caution.

  • Beginner Dosage: NOT RECOMMENDED. S-23 is strictly for experienced users with multiple prior SARM or steroid cycles.
  • Intermediate/Advanced Dosage: 10-20 mg per day. A common starting point is 10mg (one tablet) split into two 5mg doses. This can be increased to 15-20mg for more advanced users.
  • Expert Dosage: 20-25 mg per day. Doses at this level produce dramatic results but come with a severe increase in suppression and side effects. Not recommended without a testosterone base.

Cycle length should be limited to 6-8 weeks due to its high level of suppression and potential hepatotoxicity. A comprehensive Post Cycle Therapy (PCT) is absolutely mandatory after any S-23 cycle.

Advanced S-23 Cycle Stacking

S-23 is a cornerstone of advanced cutting and hardening stacks. Its power is best utilized when combined with other compounds that complement its aggressive profile.

  • The Ultimate Pre-Contest Stack: Combine S-23 with YK-11 and GW501516 (Cardarine). YK-11 inhibits myostatin for unprecedented fullness, while Cardarine provides the endurance for brutal cardio sessions, creating the ultimate shredded and grainy physique.
  • Aggressive Cutting Stack: For extreme fat loss, stack S-23 with T3 (Cytomel) and Clenbuterol. This trio creates a massive thermogenic and metabolic effect, but must be carefully monitored due to its intensity.
  • Elite Hardening Stack: Stack S-23 with Masteron 200 and a low dose of Testosterone Propionate. This combination provides multiple pathways for achieving extreme dryness, hardness, and vascularity, perfect for the final weeks before a show.
  • Strength and Power Stack: For athletes focused on performance, stack S-23 with RAD-140 (Testolone). This SARM-only stack yields incredible strength and power, but suppression will be severe, requiring a robust PCT.
  • Testosterone Base Stack: The most responsible way to run S-23 is on a base of Testosterone. This prevents the symptoms of complete suppression (lethargy, low libido) and provides a stable hormonal foundation for the cycle. An AI like Aromasin may be needed.

Possible Side Effects of S-23

S-23's side effects are significant and must be thoroughly understood before use. Its profile is closer to that of a steroid than a typical SARM.

  • Severe Testosterone Suppression: S-23 is highly suppressive and will shut down natural testosterone production completely, even at moderate doses. A strong PCT with Clomid and Nolvadex is non-negotiable. Using a testosterone base is highly recommended.
  • Androgenic Side Effects: Due to its androgenic nature, S-23 can cause acne, accelerated hair loss (in those predisposed to male pattern baldness), and increased body hair growth.
  • Potential for Gynecomastia: Its progestogenic activity means S-23 can potentially cause gynecomastia (estrogen-related) in sensitive individuals, especially when stacked with other aromatizing compounds. Having an AI on hand is prudent.
  • Liver Toxicity: S-23 is hepatotoxic. It is a 17-alpha alkylated oral compound, making it stressful to the liver. Cycle length must be limited, and liver support supplements (TUDCA, NAC) are essential.
  • Negative Lipid Profile Impact: S-23 can significantly worsen cholesterol levels, lowering HDL (good) and raising LDL (bad) cholesterol. Cardiovascular health must be monitored.
  • Vision Side Effects: Some users report minor, temporary vision issues such as difficulty adjusting to darkness, similar to but typically less severe than those associated with S4.

Why Dragon Pharma S-23 is the Professional's Choice

When using a compound as potent and demanding as S-23, there is no room for underdosed or impure products. Dragon Pharma's commitment to quality is your guarantee of safety and efficacy. Our most recent lab test reveals a potency of 12.43mg per tablet—significantly overfilled to ensure you experience the full, uncompromising power of Mastorin. This level of transparency and reliability is what separates Dragon Pharma from the competition. When you choose our S-23, you are not experimenting; you are deploying a verified, elite-level tool to achieve the ultimate level of conditioning.

S-23 Profile

Name: Mastorin, S-23
Drug Class: SARM (Selective Androgen Receptor Modulator)
Other common names and terms: S-23, Mastorin
Active Life: 12-16 hours
Detection Time: ~4 weeks
Chemical Structure</strong]: (S)-N-(4-cyano-3-(trifluoromethyl)phenyl)-3-(3-cyanophenoxy)-2-hydroxy-2-methylpropanamide
Common Doses:
10-25 mg/day
Blood pressure:
Can increase
Acne:
Likely (androgenic)
Water retention:
None (causes dryness)
Aromatisation:
No (but has progestogenic activity)
Liver toxicity:
Yes (C17-aa alkylated)
Decrease HPTA function:
Yes (highly suppressive)

Third Party Lab Test Results

Dragon Pharma S-23 Lab Test Report April 2025
2025-04-18
12.43 mg/tab
Dragon Pharma S-23 Lab Test Report January 2024
2024-01-03
9.97 mg/tab

Is S-23 the most powerful SARM available?

Yes, S-23 is widely regarded as one of the most potent SARMs available, alongside YK-11. Its power comes from its strong anabolic and androgenic rating, as well as its unique progestogenic activity. The effects on muscle hardness, fat loss, and strength are more pronounced and comparable to mild anabolic steroids rather than typical SARMs like Ostarine or Ligandrol. This is why it is strictly recommended for experienced users who understand how to manage its significant side effect profile.

Do I need a testosterone base when using S-23?

It is highly recommended. S-23 is profoundly suppressive and will shut down your natural testosterone production. Running it without a testosterone base will lead to symptoms of hypogonadism, including severe lethargy, low libido, depression, and joint pain. Using a testosterone base (e.g., Testosterone Enanthate or Cypionate at 200-300mg/week) provides your body with a stable source of testosterone and its metabolite estrogen, preventing these negative symptoms and creating a more productive and enjoyable cycle.

What is the difference between S-23 and other cutting SARMs like Ostarine?

The difference is in both potency and mechanism. Ostarine is mild, minimally suppressive, and provides gentle muscle preservation and fat loss. S-23, in contrast, is aggressively anabolic and androgenic. It provides dramatic hardening, extreme fat loss, and significant strength gains. Crucially, S-23 is highly suppressive and liver-toxic, whereas Ostarine is not. Think of Ostarine as a versatile tool for general fitness, while S-23 is a specialized, professional-grade weapon for achieving peak conditioning.

Can women use S-23?

Absolutely not. S-23 is strictly for male use only. Its potent androgenic and progestogenic properties make the risk of virilization (development of male characteristics such as voice deepening, body hair growth, and clitoral enlargement) extremely high. Even at micro-doses, the risk is unacceptable. Women seeking similar cutting effects should consider much milder compounds like Ostarine (MK-2866) or Anavar.

What makes S-23's progestogenic activity significant?

Progestogenic activity is rare among SARMs and is more commonly associated with steroids like Trenbolone and Nandrolone. This activity can synergize with estrogen in the breast tissue, potentially increasing the risk of gynecomastia in individuals who are sensitive. It also may contribute to the strong anabolic and hardening effects of the compound. This unique property is why users must be vigilant and have anti-estrogen medications (Aromatase Inhibitors) on hand, especially when stacking S-23 with aromatizing compounds like testosterone.

S 23 10 mg Reviews
Joshua Harris
September 13, 2024

I noticed an improvement in muscle retention and strength with S-23. My workouts are more effective, and I feel energized.

Ethan Anderson
August 30, 2024

Dragon Pharma's S-23 has been vital in my cutting phase. It has helped me maintain my muscle mass while my body fat percentage dropped.

Matthew Martinez
August 16, 2024

My strength increased significantly with S-23. It gave me better muscle retention and energy throughout my training sessions.

Daniel Thompson
August 2, 2024

S-23 from Dragon Pharma is the perfect option for anyone wanting to build muscle and lose fat simultaneously. It helped me achieve my physique goals.

Christopher Parker
July 19, 2024

I've used S-23 to improve muscle definition while cutting. My muscles look more defined, and my stamina has increased noticeably.

Jacob Scott
July 5, 2024

S-23 helped me keep muscle mass while cutting. My strength has improved, and my workouts are more intense.

Andrew Harris
June 21, 2024

Dragon Pharma's S-23 has been great for my physique. I've gained muscle mass while staying lean and have more energy during workouts.

Michael Wilson
June 7, 2024

I've been using S-23 for a few months, and my muscles are more defined and fuller. My energy levels are high, and I feel much stronger.

James Robinson
May 24, 2024

S-23 gave me lean muscle gains while keeping my body fat low. It's an excellent option for cutting and maintaining muscle mass.

David Johnson
May 10, 2024

Dragon Pharma's S-23 provided me with significant strength gains. I've noticed an improvement in muscle definition, and my endurance has increased.

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