IGF-1 LR3 1 mg

Dragon Pharma IGF-1 LR3 1 mg: The Ultimate Long-Acting Growth Factor for Hyperplasia and Nutrient Partitioning

For bodybuilders and athletes seeking to push beyond the limits of standard hypertrophy, Dragon Pharma IGF-1 LR3 1 mg offers a revolutionary approach to muscle development. This product contains a modified, more potent, and significantly longer-lasting version of Insulin-like Growth Factor-1. The "LR3" designation refers to the Long R3 analog, which has been engineered with an amino acid substitution that reduces its binding to IGF-binding proteins in the bloodstream. This crucial modification gives it a half-life of 20-30 hours—compared to just minutes for natural IGF-1—and greatly increases its bioavailability and potency. Third-party lab-verified at 1.05 mg per vial, this product delivers a powerful, sustained anabolic signal that not only promotes muscle cell growth (hypertrophy) but can also stimulate the creation of new muscle cells (hyperplasia), a phenomenon rarely achievable with other compounds. For those pursuing unparalleled fullness, rapid recovery, and next-level muscularity, IGF-1 LR3 is in a class of its own.

Effects and Benefits of IGF-1 LR3

IGF-1 LR3 operates through multiple powerful mechanisms to transform body composition and performance. Its primary action is binding to IGF-1 receptors on muscle cells, triggering a cascade of anabolic events including enhanced amino acid uptake, increased protein synthesis, and elevated glucose transport into cells. This leads to rapid and high-quality muscle growth with a characteristic "full" and "round" appearance. Unlike steroids that primarily cause hypertrophy (enlargement of existing cells), IGF-1 LR3 is one of the few substances believed to promote hyperplasia—the actual splitting and creation of new muscle cells—which can permanently increase one's capacity for muscle growth. Furthermore, it exhibits powerful nutrient-partitioning effects, shuttling carbohydrates and amino acids directly into muscle tissue while inhibiting glucose uptake into fat cells, resulting in simultaneous muscle growth and fat loss. Its benefits extend to dramatically accelerated recovery from intense training by reducing muscle soreness and repairing micro-tears quickly. It also strengthens connective tissues, bones, and can improve skin quality. The role of the IGF-1 axis in skeletal muscle growth is well-established, with research highlighting its critical function in regulating both muscle mass and metabolism.

Dosage and Administration Protocol

Dragon Pharma IGF-1 LR3 1 mg is supplied as a lyophilized powder that must be reconstituted with a slightly acidic solution, such as Bacteriostatic Water containing 0.9% benzyl alcohol, which helps maintain the peptide's stability.

Reconstitution: Inject 1-2 mL of Bacteriostatic Water into the vial. Gently swirl until the powder is fully dissolved; do not shake. Once reconstituted, store the vial in the refrigerator. For maximum stability, some users prefer to add acetic acid to the water, but standard bacteriostatic water is sufficient for most applications.

Common Dosing Protocol: Due to its long half-life, IGF-1 LR3 is typically administered once per day. A standard and effective dose ranges from 20 mcg to 50 mcg for beginners, with advanced users sometimes venturing up to 80-100 mcg daily. This means one 1 mg (1000 mcg) vial provides 20-50 doses. The most common and effective method of administration is subcutaneous (SubQ) injection. For localized "site enhancement," it can be injected intramuscularly (IM) into a specific muscle group post-workout. Cycles typically last 4-6 weeks, followed by an equal break to prevent receptor desensitization.

Incorporating IGF-1 LR3 into Your Anabolic Cycle

IGF-1 LR3 is an incredibly versatile compound that can be the centerpiece of a growth phase or used to enhance the effects of other anabolics. Its nutrient-shuttling properties make it particularly valuable.

• The Ultimate Mass Stack: The synergy between IGF-1 LR3 and insulin is legendary in advanced bodybuilding circles. When used together under strict protocol (and extreme caution), they create an unparalleled anabolic environment for nutrient partitioning. A safer, yet highly effective stack combines IGF-1 LR3 with powerful androgens like Testabol 400 and Deca 300 for massive, synergistic gains.
• GH and IGF-1 Synergy Stack: For a top-tier peptide cycle, stack IGF-1 LR3 with genuine Human Growth Hormone like Dragontropin. HGH stimulates the liver to produce IGF-1, and adding exogenous IGF-1 LR3 creates a powerful feedback loop that maximizes growth and fat loss from both ends of the axis.
• Site Enhancement and Lagging Body Part Training: One of the unique applications of IGF-1 LR3 is intramuscular injection for site growth. Post-workout, inject 20-40 mcg IM into a lagging muscle group like calves, shoulders, or arms. This can be combined with other site-enhancement protocols using compounds like Suspension 100 for targeted growth.
• Cutting and Pre-Contest Stack: During a calorie deficit, IGF-1 LR3 helps preserve lean mass while promoting fat loss. Stack it with a fat-burning agent like Clenbuterol and a thyroid hormone like T3 to achieve a shredded, full look on stage.

Possible Side Effects and Safety

While IGF-1 LR3 is a potent and effective peptide, it must be used with respect and caution due to its powerful hypoglycemic and growth-promoting effects.

• Hypoglycemia: This is the most common and potentially dangerous side effect. IGF-1 LR3 significantly increases glucose uptake into cells, which can cause a sharp drop in blood sugar. Symptoms include sweating, shaking, dizziness, confusion, and hunger. It is crucial to time injections around carbohydrate-rich meals and have a fast-acting sugar source on hand.
• Organ Growth: As a systemic growth factor, there is a theoretical risk of internal organ enlargement (splanchnomegaly) with prolonged, high-dose use. This is why cycling is imperative, and doses should be kept within reasonable limits.
• Water Retention: Some users experience mild to moderate water retention, which typically subsides after the first week or two of use.
• Numbness and Tingling: Due to its effects on nerve growth, some users report transient tingling sensations, particularly in the hands (carpal tunnel-like symptoms).
• Increased Hunger: The hypoglycemic effect can trigger intense hunger as the body signals for more fuel.
• Acromegaly-like Symptoms: Long-term abuse at very high doses could potentially lead to bone growth in the jaw, hands, and feet. This is avoidable with sensible dosing and cycling.
• No HPTA Suppression: IGF-1 LR3 does not suppress the hypothalamic-pituitary-testicular axis and has no androgenic or estrogenic side effects.

Starting with a low dose (20 mcg) to assess your body's response, particularly to hypoglycemia, is absolutely essential for safe use.

IGF-1 LR3 Profile

Name: Insulin-like Growth Factor 1 Long R3
Drug Class: Long-Acting Growth Factor Peptide
Other common names and terms: Long R3 IGF-1, IGF-1 Analog
Active Life: 20-30 hours
Detection Time: Several days
Chemical Structure: 83-amino acid polypeptide with Arg3 substitution
Common Doses: 20-50 mcg per day, once daily
Blood pressure: Can cause a slight increase due to water retention
Acne: Rare, but possible due to increased growth factor activity
Water retention: Common, especially at the beginning of a cycle
Aromatisation: No
Liver toxicity: None
Decrease HPTA function: No

Third Party Lab Test Results

2024-01-19

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1.05 mg