IGF-1 LR3 1 mg
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IGF-1 LR3 1 mg

Drug Class: Long-Acting Peptide Hormone
Composition: Insulin-like Growth Factor 1 Long R3
Dosage: 1 mg/vial
Form: Lyophilized (Freeze-Dried) Powder
Unit: 2 mL Vial
Brand: Peptide Hubs
For Research and Laboratory Use Only

Out of stock

IGF-1 LR3: The Ultimate Guide to Muscle Growth and Recovery

For bodybuilders and athletes relentlessly pursuing the next level of performance, IGF-1 LR3 stands as a pinnacle of peptide science. Peptide Hubs is proud to offer a pure, third-party tested 1 mg vial of this powerful growth factor, designed for researchers exploring the frontiers of hypertrophy and recovery. This long-acting analog of Insulin-like Growth Factor-1 offers a unique mechanism for promoting cellular growth, making it a subject of intense interest in the fitness community.

What is IGF-1 LR3?

IGF-1 LR3 (Long R3 Insulin-like Growth Factor) is a synthetically modified version of the natural IGF-1 hormone. It has been engineered for a significantly longer half-life and reduced binding to proteins in the bloodstream, resulting in greater bioavailability and a more potent anabolic effect. Unlike its natural counterpart, which is produced primarily in the liver, IGF-1 LR3 can be administered to target specific muscle groups or systemically for whole-body effects. Its primary role is to stimulate the growth and differentiation of various cells, most notably skeletal muscle cells, which is why it's a key topic of discussion among advanced physique enhancers. For a deeper scientific understanding, you can refer to this authoritative source on IGF-1 LR3's chemical data and structure at PubChem.

Effects of IGF-1 LR3

The effects of IGF-1 LR3 are what make it so sought-after. Users report significant and tangible benefits that directly contribute to their fitness goals.

  • Pronounced Muscle Hyperplasia & Hypertrophy: IGF-1 LR3 doesn't just enlarge existing muscle cells (hypertrophy); it may also stimulate the creation of new ones (hyperplasia), a rare and powerful effect.
  • Dramatically Enhanced Recovery: By accelerating the repair of muscle tissue damaged during intense training, IGF-1 LR3 reduces downtime and allows for more frequent, high-intensity sessions.
  • Significant Fat Loss: It promotes nutrient partitioning, shuttling glucose and amino acids into muscle cells while enhancing lipolysis (fat breakdown).
  • Improved Nutrient Uptake: Similar to insulin, it increases the uptake of glucose and amino acids into cells, creating a highly anabolic internal environment.
  • Joint and Connective Tissue Repair: It stimulates the growth of cartilage, tendons, and ligaments, helping to heal old injuries and prevent new ones.

Dosage and Administration

Proper dosing is critical for achieving desired results while minimizing potential side effects. IGF-1 LR3 is typically reconstituted with Bac Water (Bacteriostatic Water) to create an injectable solution. The most common research dosage ranges from 20 mcg to 50 mcg per day. Beginners are strongly advised to start at the lower end of this spectrum (20-30 mcg/day) to assess tolerance. More experienced researchers may explore doses up to 50-80 mcg/day. Administration is typically done via subcutaneous (SubQ) injection. Some advanced protocols involve intramuscular (IM) injections post-workout to target specific muscle groups, a practice known as "site growth." The total cycle length is generally 4-6 weeks to prevent receptor desensitization.

IGF-1 LR3 Cycle Guide

To maximize the effectiveness of an IGF-1 LR3 cycle, it is often stacked with other complementary peptides and compounds. This synergistic approach can amplify results in muscle growth, fat loss, and recovery. A well-planned 6-week cycle could look like this:

  • IGF-1 LR3: 40 mcg daily, injected post-workout.
  • For Enhanced Growth Hormone Pulse: Stacking with a secretagogue like CJC-1295/Ipamorelin can create a powerful synergy, boosting the body's own GH and IGF-1 production alongside the exogenous LR3.
  • For Accelerated Injury Healing: Adding TB-500 5 mg can provide unparalleled support for tendon, ligament, and muscle repair, making it ideal for those pushing through intense training loads.
  • For Potent Fat Loss Synergy: Combining with AOD 9604 5 mg can create a powerful fat-burning stack, as both compounds are highly effective at promoting lipolysis.
  • For Systemic Recovery and Gut Health: Incorporating BPC-157 5 mg can offer comprehensive healing benefits for the entire body, including the gastrointestinal tract.
  • For Post-Cycle Therapy (PCT) Support: After a potent cycle, a peptide like GHK-Cu 50 mg can be excellent for overall systemic recovery, collagen synthesis, and anti-aging benefits.

Possible Side Effects

While IGF-1 LR3 is generally well-tolerated when used responsibly, potential side effects exist and must be considered.

  • Hypoglycemia: This is the most common side effect. Due to its insulin-like activity, blood sugar levels can drop. It is crucial to consume a carbohydrate source around the time of injection.
  • Organ Growth: There is a theoretical risk of internal organ enlargement (splanchnomegaly) with prolonged, high-dose use. This is why cycle length should be strictly limited.
  • Numbness and Tingling: Some users report carpal tunnel-like symptoms or tingling due to potential fluid accumulation in connective tissues.
  • Headaches and Lethargy: These can occur, often linked to hypoglycemia.
  • Increased Cancer Risk: IGF-1 is a growth factor, and its use could potentially accelerate the growth of pre-existing malignancies. It is absolutely contraindicated for anyone with a history of or active cancer.

Reconstitution and Storage

Your Peptide Hubs IGF-1 LR3 arrives as a lyophilized powder in a 2 mL vial. To prepare it for research, gently inject 1-2 mL of Bac Water into the vial, aiming the stream against the glass wall to avoid agitating the peptide. Roll the vial gently between your hands until the powder is fully dissolved. Do not shake, as this can damage the fragile peptide structure. Once reconstituted, the solution must be refrigerated and used within a few weeks for optimal potency. Unreconstituted vials should be stored in a cool, dark place, ideally in a refrigerator.

IGF-1 LR3 1 mg Profile

Name: IGF-1 Long R3
Drug Class: Long-Acting Peptide Hormone
Other common names and terms: Insulin-like Growth Factor 1 Long R3, Long R3 IGF-1, LR3IGF-1
Active Life: 20-30 hours
Detection Time: Not well established for athletic testing, but likely short due to peptide nature.
Chemical Structure: Modified 83 amino acid polypeptide
Common Doses: 20-50 mcg per day for research purposes
Blood pressure: Typically no direct impact
Acne: Rare
Water retention: Possible, mild
Aromatisation: No (does not convert to estrogen)
Liver toxicity: No
Decrease HPTA function: No direct impact on the hypothalamic-pituitary-testicular axis

Is IGF-1 LR3 legal to buy in the USA?

In the United States, IGF-1 LR3 is legally sold for research and laboratory use only. It is not approved by the FDA for human consumption, diagnosis, or the treatment of any disease. It is the responsibility of the purchaser to ensure their compliance with all local, state, and federal laws regarding the possession and use of research chemicals.

What is the difference between IGF-1 LR3 and regular IGF-1?

The key difference lies in the structure and activity. IGF-1 LR3 has an amino acid substitution (Arg3) and a 13-amino acid extension peptide, which makes it resistant to binding to IGF Binding Proteins (IGFBPs). This results in a much longer half-life (20-30 hours vs. a few minutes for regular IGF-1) and significantly greater bioavailability and potency in a research setting.

How should I store my IGF-1 LR3 vial?

Unreconstituted vials of IGF-1 LR3 should be stored in a refrigerator (2-8°C or 36-46°F) in a dark place. Once you have reconstituted the peptide with Bacteriostatic Water, it must be refrigerated and used within a few weeks to ensure stability and potency. Avoid freezing or shaking the reconstituted solution.

Can IGF-1 LR3 cause low blood sugar?

Yes, hypoglycemia (low blood sugar) is the most frequently reported side effect. IGF-1 LR3 has insulin-like effects and increases glucose uptake into cells. To prevent this, it is highly recommended to administer the peptide with or shortly after a meal containing carbohydrates. Having a quick sugar source on hand is also a prudent safety measure.

Why is Peptide Hubs the best source to buy IGF-1 LR3 in the USA?

Peptide Hubs is committed to providing the highest purity research compounds. Our IGF-1 LR3 is produced in ISO-certified facilities, undergoes rigorous third-party testing for purity and concentration, and is shipped discreetly from within the USA for fast delivery. We provide transparent data and support for the research community, ensuring you receive a reliable and potent product for your studies.

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