PT-141 10 mg

PT-141 10 mg: The Ultimate Libido and Sexual Enhancement Peptide

For bodybuilders, fitness enthusiasts, and anyone looking to revitalize their sexual health, Peptide Hubs PT-141 (Bremelanotide) offers a revolutionary approach. Unlike traditional solutions that work on hormones or blood flow, PT-141 directly targets the central nervous system to activate sexual arousal pathways. This 10 mg vial of high-purity, lab-tested lyophilized powder is your key to unlocking a powerful, reliable, and on-demand libido boost for both men and women, helping you overcome the sexual side effects often associated with intense training cycles or lifestyle stress.

What is PT-141 (Bremelanotide)?

PT-141 is a synthetic peptide analog of α-MSH (alpha-melanocyte-stimulating hormone). It is a metabolite of the well-known peptide Melanotan 2, but with a crucial difference: it has been specifically engineered to enhance libido without the strong melanotropic (tanning) effects. It was developed from research into Melanotan II and gained attention for its ability to treat sexual dysfunction in both sexes. Its mechanism of action is unique; it bypasses the hormonal pathways and acts directly on melanocortin receptors in the central nervous system, particularly in the hypothalamus, which is responsible for regulating sexual arousal. The U.S. Food and Drug Administration (FDA) approved Bremelanotide (under the brand name Vyleesi) in 2019 for premenopausal women with acquired, generalized hypoactive sexual desire disorder (HSDD), validating its powerful effect on female libido.

Effects of PT-141

The effects of PT-141 are primarily neurological, leading to profound physiological and psychological changes related to sexual function. Users report a significant and often spontaneous increase in libido and improvement in sexual performance.

• Powerful Libido Enhancement: PT-141's primary effect is a robust increase in sexual desire. It can spontaneously generate feelings of arousal, often described as a "mental" horniness, rather than a purely physical reaction. This makes it effective for both psychological and physiological forms of low libido.
• Improved Erectile Function in Men: For men, PT-141 can lead to stronger, more frequent, and longer-lasting erections. It is particularly noted for its ability to help achieve erections even in cases where PDE5 inhibitors (like Viagra or Cialis) have failed, as it works through a completely different mechanism.
• Enhanced Sexual Arousal & Sensation in Women: Women using PT-141 report a marked increase in sexual desire and spontaneous arousal. It also enhances genital sensitivity and can improve the ability to achieve orgasm, making it a powerful tool for treating female sexual dysfunction.
• Spontaneous and Prolonged Arousal: The effects are not dependent on physical stimulation to begin. Arousal can occur spontaneously after the peptide takes effect. Furthermore, the window of enhanced libido can last for several hours, providing a flexible and prolonged experience.
• Non-Hormonal Action: Since PT-141 does not work by altering hormone levels (like testosterone or estrogen), it does not contribute to hormonal imbalances or suppress natural production, making it a safer option to stack with other performance-enhancing compounds.

Dosage and Administration

PT-141 is supplied as a lyophilized powder that must be reconstituted with Bacteriostatic Water before subcutaneous (SubQ) injection. Intramuscular (IM) injection is not common for this peptide.

Reconstitution Guide:

1. Gently swab the rubber stoppers of both the PT-141 vial and the Bac Water vial with an alcohol prep pad.
2. Draw 1-2 mL of Bacteriostatic Water into a sterile insulin syringe.
3. Slowly inject the water down the side of the PT-141 vial, avoiding directing the stream directly onto the powder.
4. Swirl the vial gently until the powder is fully dissolved. DO NOT SHAKE.
5. The resulting solution should be clear. Refrigerate the reconstituted vial at 36-46°F (2-8°C) and use it within a few weeks.

Dosing Recommendations:

• Beginner Dose (Men & Women): 0.5 mg to 1.0 mg. It is critical to start low to assess individual tolerance, particularly to side effects like nausea.
• Effective Dose (Men): 1.5 mg to 2.0 mg is the standard effective range for most men.
• Effective Dose (Women): 1.0 mg to 1.75 mg is the standard effective range for most women.
• Maximum Dose: Do not exceed 2.0 mg in a single dose. Higher doses significantly increase the likelihood and severity of side effects without providing a proportional increase in benefits.

Administration Timing: Inject subcutaneously into the abdomen or thigh approximately 4-6 hours before sexual activity. The effects can last for up to 12-24 hours, with the peak effects typically felt within the first few hours.

PT-141 Cycle Guide

PT-141 is not a peptide for daily use. It is an "on-demand" product used in conjunction with planned sexual activity. However, it can be strategically combined with other peptides to create a comprehensive wellness and performance stack that addresses both sexual health and overall physical conditioning.

• Libido Optimization & Stress Resilience Cycle: Use PT-141 (1.5-2.0 mg) as needed. To combat the physical and mental stress of intense training that can lower libido, stack with Selank for its anxiolytic and nootropic benefits. For overall cellular repair and anti-aging support, add Epitalon.
• Post-Cycle Therapy (PCT) & Vitality Stack: After a suppressive steroid cycle, libido can be low. Use PT-141 as needed to maintain sexual function while your natural hormones recover. Support this recovery directly with Kisspeptin-10, a powerful stimulator of GnRH, which can boost natural testosterone and LH production. For general well-being, include NAD+ to support cellular energy and metabolism.
• Comprehensive Body Recomposition & Wellness: For those on a cutting cycle, use PT-141 to maintain libido while in a caloric deficit. Pair it with AOD 9604 for enhanced fat loss. To manage the potential flushing or blood pressure effects, the vasoregulatory peptide B7-33 could be a beneficial research addition.

Possible Side Effects

PT-141 is generally well-tolerated, but its unique mechanism of action can produce some transient side effects. These are almost always dose-dependent and can be minimized by starting with a low dose.

• Nausea: This is the most common side effect. It is typically mild to moderate, transient, and often diminishes with subsequent uses. Taking the dose on an empty stomach can help reduce the severity.
• Facial Flushing: A temporary reddening of the face, neck, and/or chest due to vasodilation. This is harmless and usually subsides within an hour or two.
• Spontaneous Stretching and Yawning: A curious but harmless side effect related to its action on the central nervous system. Many users report involuntary stretching spells shortly after injection.
• Headache and Dizziness: Some users may experience a mild, temporary headache or slight dizziness.
• Increased Blood Pressure: A temporary and mild increase in blood pressure can occur. Individuals with pre-existing hypertension should use caution and consult a physician.

Contraindication: PT-141 is not recommended for individuals with cardiovascular disease or uncontrolled high blood pressure. It should not be used by pregnant or nursing women.

PT-141 Profile

Name: Bremelanotide
Drug Class: Melanocortin Receptor Agonist
Other common names and terms: PT-141, Vyleesi (pharmaceutical brand)
Active Life: 4-6 hours (primary effects), up to 24 hours (residual effects)
Detection Time: Not well established, estimated 24-48 hours
Chemical Structure: Synthetic heptapeptide analog of α-MSH
Common Doses: 0.5 mg - 2.0 mg, as needed
Blood pressure: May cause a temporary, mild increase
Acne: None
Water retention: None
Aromatisation: Does not aromatize
Liver toxicity: None
Decrease HPTA function: No, it is non-hormonal

Third Party Lab Test Results

2025-04-22

View Result

11.78 mg