Drug Class: Synthetic Melanocortin Peptide
Composition: Melanotan II
Dosage: 10 mg/vial
Form: Lyophilized (Freeze-Dried) Powder
Unit: 2 mL Vial
Brand: Peptide Hubs
Laboratory Test: View Lab Report
For Research and Laboratory Use Only
Melanotan 2 represents a revolutionary breakthrough in peptide science, offering a suite of effects that extend far beyond simple skin pigmentation. As a synthetic analog of the natural alpha-melanocyte-stimulating hormone (α-MSH), it activates melanocortin receptors throughout the body. Peptide Hubs provides a premium 10 mg vial of Melanotan 2, rigorously third-party tested to ensure researchers receive a product of uncompromising purity and potency for studying its multifaceted applications.
Melanotan 2 (MT-2) is a synthetic cyclic heptapeptide (a chain of seven amino acids in a ring structure) designed to mimic the effects of α-MSH. Its primary action is binding to melanocortin receptors (MCRs), particularly MC1R in the skin, which triggers the production of eumelanin—the dark brown/black pigment responsible for a tan. Unlike MC1R, which is primarily found in the skin, other receptors like MC3R and MC4R are distributed in the brain and other tissues, explaining MT-2's diverse effects on libido, appetite, and energy expenditure. Initially researched for its potential to protect against skin cancer by stimulating a protective tan, its other potent secondary effects quickly became apparent. For a detailed biochemical analysis, you can review the Melanotan II chemical data on PubChem.
The effects of Melanotan 2 are profound and multi-systemic, making it a subject of intense interest for researchers exploring photoprotection, sexual health, and metabolism.
Melanotan 2 is typically reconstituted with Bac Water and administered via subcutaneous (SubQ) injection. Dosing is highly individual and should follow a careful protocol to minimize side effects. A standard research protocol involves a "loading phase" to build up melanin levels, followed by a "maintenance phase."
While Melanotan 2 is powerful on its own, it can be stacked with other peptides to target specific research goals, from body composition to overall wellness.
Melanotan 2 is a potent peptide, and side effects are common, especially during the initial phase. Most are transient and diminish with continued use.
Your Peptide Hubs Melanotan 2 10 mg vial arrives as a lyophilized powder. To reconstitute, gently inject 1-2 mL of Bacteriostatic Water (Bac Water) into the vial, aiming the stream against the glass wall. Roll the vial gently between your hands until the powder is completely dissolved. Do not shake, as this can damage the peptide's structure. Once reconstituted, the solution must be refrigerated and used within a few weeks. Unreconstituted vials should be stored in a cool, dark place, ideally in a refrigerator, to maintain long-term stability.
Name: Melanotan II
Drug Class: Synthetic Melanocortin Agonist
Other common names and terms: MT-2, Melanotan 2, Afamelanotide analog
Active Life: Approximately 36 hours
Detection Time: Not well established; likely short due to peptide nature.
Chemical Structure: Cyclic heptapeptide (Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-NH2)
Common Doses: 250-500 mcg (0.25 - 0.5 mg) daily or every other day
Blood pressure: Can cause a transient increase
Acne: Rare
Water retention: No
Aromatisation: No (does not convert to estrogen)
Liver toxicity: No evidence of hepatotoxicity
Decrease HPTA function: No direct impact on the hypothalamic-pituitary-testicular axis
Initial darkening of existing moles and freckles can often be seen within the first few days. A noticeable overall tan typically develops within 1-2 weeks of consistent dosing combined with UV exposure. The libido-enhancing effects are usually felt within 30-60 minutes of the first few injections.
Nausea is the most common side effect but can be managed effectively. Start with a very low dose (100-250 mcg), inject right before bedtime so you sleep through the worst of it, and always administer on an empty stomach. The body usually develops a tolerance to the nausea within 1-2 weeks.
No, they are related but distinct. PT-141 (Bremelanotide) is a metabolite of Melanotan 2 that was specifically developed to isolate the libido-enhancing effects while minimizing the tanning effects. Melanotan 2 provides both significant tanning and libido enhancement, while PT-141 is primarily focused on sexual function.
This is a normal and expected response. Melanotan 2 stimulates all melanocytes (pigment-producing cells) in the body. The melanocytes in moles and freckles are often more active or clustered, so they respond more dramatically to the peptide. It is crucial to monitor these spots for any abnormal changes and consult a dermatologist if you have concerns.
While you will develop some color without UV exposure due to the direct stimulation of melanocytes, the tan will be significantly darker, richer, and more even with minimal UV exposure. The peptide works by priming your skin to produce melanin, and UV light is the trigger that releases it. Very short, controlled exposures are all that is needed.
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Drug Class: Synthetic Melanocortin Agonist Peptide
Composition: Melanotan II
Dosage: 10 mg/vial
Form: Lyophilized Powder
Unit: 2 mL Vial
Brand: Dragon Pharma
Laboratory Test: View Lab Report
For Injectable Use After Reconstitution
Drug Class: Synthetic Melanocortin Agonist Peptide
Composition: Melanotan II
Dosage: 5 mg/vial
Form: Lyophilized Powder
Unit: 2 mL Vial
Brand: Dragon Pharma
Laboratory Test: View Lab Report
For Injectable Use After Reconstitution
For Intramuscular Injection
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Mixed Dosage: 350 mg/1 mL
Unit: 10 mL Multidose Vial
Manufactured by Kalpa Pharmaceuticals