LL-37 5 mg

LL-37 5 mg (CAP-18 Cathelicidin) – Peptide Hubs (2 mL Vial)

Peptide Hubs LL-37 5 mg (the active human cathelicidin fragment derived from CAP-18) is a lyophilized, research-grade peptide supplied in a sterile 2 mL vial for qualified laboratory use. LL-37 is widely discussed in the context of innate immunity and cell-surface interface biology in experimental models, where it is examined for roles in barrier environments and immune signaling. This 5 mg presentation is designed for pilot studies, method development, and short-horizon protocols that value precise reconstitution and minimal waste.

Important: The information below is provided for educational discussion within a lawful research context. This product is not a drug, food, or cosmetic and is not intended to diagnose, treat, cure, or prevent any disease. Purchase and use assume qualified individuals or laboratories operating under applicable regulations and SOPs.

What Is LL-37 (Cathelicidin) in the Research Setting?

LL-37 is the only human cathelicidin peptide identified to date, generated by proteolytic processing of the CAP-18 precursor. In test systems, LL-37 is explored for its membrane-interaction behavior and its participation in innate immune signaling pathways under controlled conditions. For a concise primer on innate immunity that helps frame sampling windows, endpoints, and study design, see the NCBI/Bookshelf overview on the innate immune system here.

Why Choose the 5 mg Strength?

The 5 mg vial is ideal for labs building SOPs and dialing in timing, solvent volume, storage routines, and handling consistency. Smaller fills allow you to:

• Establish round-number working concentrations that simplify micro-measurement.
• Minimize reconstitution waste during method development or multi-window pilots.
• Run A/B comparisons (e.g., timing relative to training stimulus) without opening large lots.

Once your timing, storage, and record-keeping are validated, your team can scale to larger fills for extended timelines.

Format, Reconstitution & Storage

• Presentation: Lyophilized LL-37 (cathelicidin) 5 mg total, sterile 2 mL vial.
• Reconstitution: Use sterile technique with bacteriostatic water or a lab-approved solvent. Choose a solvent volume that yields a simple, repeatable working concentration (e.g., decimal-friendly aliquots). Pre-plan aliquots to limit repeated temperature exposure.
• Storage: Keep lyophilized vials cool, dry, and protected from light per your SOP. After reconstitution, refrigerate promptly and avoid freeze–thaw cycling. Discard if the solution becomes cloudy, discolored, or otherwise compromised.

Designing a Clean LL-37 Protocol

LL-37 is frequently studied where barrier environments and innate pathways are of interest. To generate interpretable data, anchor your protocol in consistency:

• Run-in baseline: Stabilize confounders—sleep, hydration, caloric intake, macronutrients, stimulant use, training load, and environmental exposures.
• Clocks: Fix administration and sampling times (e.g., relative to meals, training, or lights-out). Write these clocks into your SOP and apply them identically on every test day.
• Measurement hygiene: Use the same devices, the same time of day, and the same conditions for body-comp proxies or recovery metrics that athletes and fitness enthusiasts often track.
• Record-keeping: Log lot numbers, solvent and volume, final concentration, aliquot size, timestamps, storage temperatures, and any deviations.

Because LL-37 is often discussed for multi-pathway effects in in vitro and ex vivo contexts, many teams prefer separate protocol arms rather than stacking mechanisms in a single arm. This preserves interpretability when you compare across dermal, tissue-recovery, metabolic, or performance-adjacent hypotheses.

Parallel Arms & Comparison Ideas (Run Separately)

• Tissue-recovery focus: Keep systemic or barrier-centric work separate from localized soft-tissue models by running a distinct arm with BPC-157 to isolate tissue-level proxies.
• Dermal/cosmetic pathways: For skin-adjacent or cosmetic endpoints, run a copper-peptide program using GHK-CU 10 mg so local outcomes don't confound innate-immunity data.
• Performance-trajectory contrast: If your cohort tracks performance or body-comp proxies, maintain a separate axis with IGF-1 LR3 1 mg to prevent mixing growth-factor signaling with innate-pathway models.
• Barrier/anti-irritation exploration: Some labs examine the tripeptide KPV 5 mg in a separate arm for irritation-adjacent proxies while keeping LL-37 data clean.
• Recovery load & volume: For training-dense cohorts, contrast with a connective-tissue program using TB-500 5 mg in its own arm; mirror training stimulus and measurement cadence.

Timing, Confounders & Data Integrity

Timing: Lock the administration-to-meal interval and administration-to-training interval so you can attribute differences to the protocol rather than lifestyle drift.

Confounders: Stabilize sleep duration/quality, hydration, caffeine/stimulants, and training volume/density. If your audience includes bodybuilders or fitness enthusiasts who vary protocols frequently, consider a "no changes" rule during the study window.

Integrity: Use checklists. Verify labels, concentration math, and timestamps. Keep chain-of-custody notes if multiple operators are involved. These details are crucial when you rerun a pilot or interpret outliers.

Quality, Authenticity & Shipping

Peptide Hubs emphasizes batch uniformity, clear labeling, and protective packaging for reliable USA transit. Our catalog structure helps teams design separate, mechanism-specific programs instead of stacking endpoints into a single arm—an approach that keeps data cleaner and more publication-ready. For buyers searching "Buy LL-37 USA" and "Peptide Hubs LL-37," this 5 mg vial offers a practical balance between precision and flexibility.

Why Choose LL-37 5 mg from Peptide Hubs?

If your lab values SOP-driven consistency, pilot-friendly fill sizes, and clean comparisons across mechanisms, LL-37 5 mg fits neatly into a rigorous workflow. The smaller fill simplifies reconstitution math, reduces waste, and lets you run multi-window pilots without tying up inventory—all with discreet, fast USA shipping and straightforward product presentation for smooth auditing.

Regulatory Notice: Not intended for human consumption. For lawful laboratory research by qualified individuals only.

Frequently Asked Questions