Epitalon 50 mg

Peptide Hubs Epitalon: The Premier Research Peptide for Cellular Longevity and Healthspan

For researchers dedicated to exploring the frontiers of aging and cellular health, Peptide Hubs presents its premium Epitalon 50 mg. This synthetic tetrapeptide, also known as Epithalon, is renowned for its potential to influence telomere length and activate the telomerase enzyme, positioning it at the cutting edge of longevity science. Sourced and stocked within the USA, our Epitalon is provided as an ultra-pure, lyophilized powder in a sterile 2 mL vial, designed for precise and reliable research outcomes.

At Peptide Hubs, we understand that groundbreaking research demands uncompromising quality. When you buy Epitalon USA from us, you are securing a research compound of the highest purity, backed by our commitment to scientific excellence and supported by fast, discreet shipping directly from the United States.

What is Epitalon?

Epitalon (or Epithalon) is a synthetic tetrapeptide with the amino acid sequence Ala-Glu-Asp-Gly. It is a laboratory-made analogue of the natural polypeptide Epithalamin, which is isolated from the pineal gland. The pioneering work of Professor Vladimir Khavinson in the early 2000s brought this peptide to prominence. Research published in the National Institutes of Health demonstrated that Epitalon could stimulate telomerase activity and extend the lifespan of human cells in culture. Its primary proposed mechanism is the epigenetic regulation of gene expression, particularly those genes involved in cellular senescence and the cell cycle.

Mechanism of Action

Epitalon's research significance lies in its multi-faceted approach to cellular aging. Its primary mechanisms of action include:

• Telomerase Activation: Epitalon is believed to promote the expression of the telomerase enzyme, which adds protective nucleotide caps (telomeres) to the ends of chromosomes. Longer telomeres are associated with greater cellular replicative capacity and youthfulness.
• Gene Expression Regulation: It appears to influence the expression of key genes involved in the cell cycle and apoptosis (programmed cell death), potentially shifting cells away from a senescent state.
• Pineal Gland Function Support: By mimicking the action of the pineal gland's own peptides, Epitalon may help normalize the production of melatonin and other neuroendocrine regulators, which often decline with age.
• Antioxidant Effects: Research suggests it may enhance the body's own antioxidant defense systems, reducing oxidative damage that contributes to aging.

Effects of Epitalon

In research models, the effects of Epitalon are associated with systemic rejuvenation and improved healthspan. Key observed outcomes include:

• Extension of Cellular Lifespan: Studies on cell cultures have shown that Epitalon can increase the number of cell divisions before senescence, a phenomenon known as the Hayflick limit.
• Improvement in Sleep-Wake Cycles: Through its action on the pineal gland, it has been reported to help restore a more youthful and regular circadian rhythm, improving sleep quality.
• Enhancement of Skin and Connective Tissue: Research notes improvements in skin elasticity, reduction of visible signs of aging, and better overall skin tone, likely due to improved fibroblast function.
• Normalization of Neuroendocrine Function: It may help rebalance age-related declines in key hormones, supporting overall metabolic and hormonal health.
• Retina and Visual Function Support: Several studies point to its potential in supporting retinal health and preserving visual acuity during the aging process.

Dosage and Administration

Important: The following information is based on historical research protocols and is provided for educational purposes only. Researchers must consult current scientific literature to determine appropriate dosages for their specific models.

Epitalon is typically administered via subcutaneous injection. Research protocols often utilize a cyclical approach rather than continuous administration. A common research dosage ranges from 5 mg to 10 mg per day.

Reconstitution: The lyophilized powder must be reconstituted with Bacteriostatic Water (Bac Water). Reconstituting a 50 mg vial with 2 mL of Bac Water yields a concentration of 25 mg per mL. A 0.2 mL injection would then deliver a 5 mg dose. For optimal results, Peptide Hubs recommends using our pharmaceutical-grade Bac Water.

Cycle and Research Stacking

Research cycles with Epitalon are typically conducted in short, intensive bursts, reflecting its role in epigenetic reprogramming rather than daily metabolic support. Common cycles last 10-30 days and are often repeated once or twice per year. Its systemic effects make it an excellent base for comprehensive longevity and performance stacks.

Here are advanced research stacks involving Peptide Hubs Epitalon:

• For Comprehensive Cellular Rejuvenation: Stack Epitalon with NAD+ 100 mg. While Epitalon works on the genetic level, NAD+ provides the essential cellular cofactor for energy production and sirtuin activation, creating a powerful synergy for metabolic and epigenetic health.
• For Cognitive and Neurological Longevity: Combine with Semax 5 mg to research the combined effects on neurogenesis, brain-derived neurotrophic factor (BDNF), and overall cognitive function protection.
• For Advanced Anti-Aging and Tissue Repair: Add GHK-Cu 50 mg to a protocol. GHK-Cu is known for its powerful effects on skin, connective tissue, and wound healing, complementing Epitalon's systemic anti-aging actions.
• For Mitochondrial and Metabolic Health: Research the synergy between Epitalon and MOTS-c 10 mg, a peptide that regulates metabolic homeostasis and mitochondrial function.
• For Sleep Optimization and Recovery: Stack with DSIP 5 mg (Delta Sleep Inducing Peptide) to study the profound effects of deep, restorative sleep on overall recovery, hormonal health, and longevity markers.

Possible Side Effects

Epitalon is considered one of the safest peptides in research, with a very high tolerance profile and no known toxicity. However, in rare instances, researchers have noted:

• Mild and Transient Drowsiness: Some reports indicate a temporary feeling of relaxation or sleepiness after administration, which often aligns with its effect on normalizing circadian rhythms.
• Changes in Sleep Patterns: As the body adjusts, some alterations in sleep architecture may be observed, typically resulting in more restful and regulated sleep over time.
• Localized Discomfort: As with any subcutaneous injection, there is a potential for minor redness, swelling, or itching at the administration site.

Critically, Epitalon does not influence sex hormone levels, has no androgenic or estrogenic activity, and does not suppress the HPTA axis. It is not known to cause water retention, acne, or liver toxicity.

Why Choose Peptide Hubs Epitalon?

Choosing to buy Epitalon USA from Peptide Hubs means investing in a research compound of exceptional purity and stability. The integrity of a peptide as delicate as Epitalon is paramount to its efficacy in sensitive research applications. Our stringent quality control and direct-from-source supply chain ensure that every 50 mg vial meets the highest standards. For researchers committed to exploring the deepest mechanisms of aging and cellular health, Peptide Hubs is your trusted partner.

Epitalon Profile

Name: Epitalon
Drug Class: Synthetic Tetrapeptide
Other common names and terms: Epithalon, Ala-Glu-Asp-Gly
Active Life: Approximately 20-30 minutes (induces long-term epigenetic changes)
Detection Time: Not well-established; very short due to rapid breakdown
Chemical Structure: L-Alanyl-L-Glutamyl-L-Asparagyl-L-Glycine
Common Doses: 5 mg - 10 mg per day
Blood pressure: No significant effect reported; may have a normalizing effect
Acne: No significant effect reported
Water retention: No significant effect reported
Aromatisation: Does not aromatize
Liver toxicity: No liver toxicity reported
Decrease HPTA function: No significant suppression of the HPTA axis